Mark Swaim, MD, PhD, on the Promising Novel Biomaterial in Cerebral Aneurysms Treatment

Mark Swaim, MD, PhD, is excited about this latest medical breakthrough.

Tim Becker, a medical device engineer, is working on a polypropylene glycol-based biomaterial or PPODA-QT. It is very similar to body tissue and can potentially help treat brain aneurysms and improve patient outcomes for potential stroke and stroke patients.

Burst without warning
An aneurysm is a bulge or a pouch that grows in a compromised wall of a blood vessel. Often unnoticed and therefore, untreated, it can burst without warning, cause bleeding in the brain and result in a stroke.

The Brain Aneurysm Foundation reports that 6.5 million Americans have unruptured brain aneurysms. Approximately 30,000 will experience a ruptured aneurysm each year. Mark Swaim, MD, PhD, emphasizes that only one in four will recover fully.

A successful plug
Becker believes that the biomaterial can successfully plug a ballooning aneurysm, allowing the tissue to regenerate over it, and cure the main vessel.

The target is the larger aneurysms, which can grow as large as a quarter, and are harder to treat. They tend to grow back within three years. With the amount of blood pressure on the fragile blood vessels, blood flow eventually finds a way back in and cause it to burst.

A more natural option
The PPODA-QT biomaterial is harmonious with the body and can plug that aneurysm gap effectively while leaving a smooth surface to allow healing. Mark Swaim, MD, PhD, adds that it’s a more natural and better option for the body compared to a wire coil.

Long term stability
The project aspires to evaluate the long-term mechanical solidity of PPODA-QT as a treatment for more giant aneurysms, and come up with delivery methods to bring the material into the aneurysms as a way to lessen the probability of their recurrence.

The goal is that aneurysms can be detected earlier, with a device that cures them not to have them regrow. As someone who has spent his life trying to improve patient outcomes, Mark Swaim MD, PhD, is hopeful in its possibility as a better aneurysm treatment option.

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